Across TCGA pan-cancer cohorts, TTC36 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TTC36 data layer compared with 26 for mass-spec protein and 1 for mutation status.
The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TTC36 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TTC36 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.
CCRCC are the cancer types where TTC36 mass-spec protein most reproducibly stratifies survival.