TTC33

Across TCGA patient cohorts, TTC33 mutation is significantly associated with the RNA expression of many other genes, with 1,280 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC33-associated genes across cancer lineages are MIR3908, DCP1A, and ZNHIT3. Each is linked with TTC33 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC33-to-partner and partner-to-TTC33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3908 grouped by TTC33-low versus TTC33-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC33→partner) and Y-score (partner→TTC33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR3908 →	+0.266	+4.882	<.001	.005	3	2
UCEC	DCP1A →	+0.559	+3.608	.008	.001	3	1
UCEC	ZNHIT3 →	+0.492	+2.606	.005	.006	3	1
UCEC	TMEM269 →	+0.232	+2.617	<.001	.006	3	1
UCEC	RN7SL650P →	+0.279	+2.359	.009	.005	3	1
UCEC	TUBGCP5 →	+0.559	+3.732	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,280 associations by consensus.

MIR3908 by TTC33 expression — LUSC

Explore this box plot interactively →