TTC33

Across TCGA cell cohorts, TTC33 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,211 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC33-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Protein localization to non-motile cilium, and Protein localization to nuclear inner membrane. Each is linked with TTC33 in more than 15 cancer types. Because this analysis shows association rather than direction, both TTC33-to-partner and partner-to-TTC33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by TTC33-low versus TTC33-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC33→partner) and Y-score (partner→TTC33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.119	+0.987	<.001	.001	3	16
LUNG_NSCLC_LUAD	Protein localization to non-motile cilium →	+0.062	+0.821	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.179	+1.167	<.001	<.001	3	12
LARGE_INTESTINE	Positive regulation of organelle assembly →	+0.070	+0.953	<.001	<.001	3	11
LARGE_INTESTINE	Intraciliary anterograde transport →	+0.081	+0.735	<.001	<.001	3	11
URINARY_TRACT	Clathrin coat disassembly →	-0.158	-0.866	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,211 associations by consensus.

Establishment of mitotic sister chromatid cohesion by TTC33 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →