TTC31

Across TCGA pan-cancer cohorts, TTC31 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TTC31 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TTC31 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TTC31 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where TTC31 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.920	0.350	.010	8	view →
CCRCC	DFS	Median	III,IV	0.078	0.856	.038	3	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.414	.024	2	view →
PDAC	OS	Tertile	All	0.500	1.000	.040	2	view →
HNSC	DFS	Median	All	1.000	0.886	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TTC31–LUAD (DFS)

Open the LUAD breakdown →