TTC31

Across TCGA cell cohorts, TTC31 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,089 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC31-associated GO terms across cancer lineages are Constitutive heterochromatin formation, Negative regulation of calcium ion export across plasma membrane, and Regulation of centriole-centriole cohesion. Each is linked with TTC31 in more than 15 cancer types. Because this analysis shows association rather than direction, both TTC31-to-partner and partner-to-TTC31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Constitutive heterochromatin formation grouped by TTC31-low versus TTC31-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC31→partner) and Y-score (partner→TTC31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Constitutive heterochromatin formation →	+0.087	+0.860	<.001	<.001	3	16
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.068	+0.632	<.001	<.001	3	16
URINARY_TRACT	Regulation of centriole-centriole cohesion →	+0.191	+1.006	<.001	<.001	3	16
BONE	Negative regulation of chromosome organization →	+0.109	+0.936	.007	<.001	2	16
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.084	+1.365	<.001	<.001	3	15
PANCREAS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.159	+0.791	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,089 associations by consensus.

Constitutive heterochromatin formation by TTC31 expression — BLOOD_Lymphoma

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