TTC31

Across TCGA cell cohorts, TTC31 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC31-associated genes across cancer lineages are IFNA8, KRT26, and SCGB1C1. Each is linked with TTC31 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC31-to-partner and partner-to-TTC31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA8 grouped by TTC31-low versus TTC31-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC31→partner) and Y-score (partner→TTC31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA8 →	+0.034	+4.930	<.001	.008	3	1
SOFT_TISSUE	KRT26 →	+0.022	+4.930	<.001	.008	3	1
SOFT_TISSUE	SCGB1C1 →	+0.073	+5.977	<.001	.001	3	1
SOFT_TISSUE	MROH5 →	+0.021	+4.930	<.001	.008	3	1
BLOOD_Leukemia	GML →	+0.057	+4.152	.007	.009	3	1
BLOOD_Leukemia	TSHB →	+0.125	+4.276	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

IFNA8 by TTC31 expression — SOFT_TISSUE

Explore this box plot interactively →