Across TCGA patient cohorts, TTC30B mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC30B-associated genes across cancer lineages are Rad50, EGFR_pY1068, and A-Raf_pS299. Each is linked with TTC30B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC30B-to-partner and partner-to-TTC30B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC30B→partner) and Y-score (partner→TTC30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.305	-2.502	.001	.002	3	2
UCEC	EGFR_pY1068 →	-0.319	-2.906	.001	.001	3	1
UCEC	A-Raf_pS299 →	-0.137	-2.000	.003	.030	3	1
UCEC	ERK2 →	+0.227	+3.321	.002	.009	3	1
UCEC	GAPDH →	+0.422	+2.321	.045	.033	3	1
UCEC	GATA6 →	-0.157	-3.307	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

TTC30B survival (RNA) · tumor vs normal (RNA) · all TTC30B data types