Across TCGA cell cohorts, TTC30B mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TTC30B-associated genes across cancer lineages are WFDC11, TSBP1, and OOSP2. Each is linked with TTC30B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC30B-to-partner and partner-to-TTC30B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC30B→partner) and Y-score (partner→TTC30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	WFDC11 →	+0.046	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	TSBP1 →	+0.092	+3.544	<.001	.009	3	1
BREAST	OOSP2 →	+0.017	+4.781	<.001	.003	3	1
BREAST	OR10J1 →	+0.425	+4.781	<.001	.003	3	1
BLOOD_Lymphoma	HOXB1 →	+0.014	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.024	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

TTC30B survival (RNA) · tumor vs normal (RNA) · all TTC30B data types