TTC29

Across TCGA cell cohorts, TTC29 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TTC29-associated genes across cancer lineages are SMIM23, OR51A4, and SMIM28. Each is linked with TTC29 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC29-to-partner and partner-to-TTC29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM23 grouped by TTC29-low versus TTC29-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC29→partner) and Y-score (partner→TTC29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SMIM23 →	+0.018	+4.437	<.001	.004	3	1
SKIN	OR51A4 →	+0.008	+4.437	<.001	.004	3	1
SKIN	SMIM28 →	+0.016	+4.437	<.001	.004	3	1
STOMACH	FGF6 →	+0.185	+3.247	<.001	.003	3	1
STOMACH	TCERG1L →	+0.026	+3.263	.001	.001	3	1
LUNG_NSCLC_LUAD	KLRF2 →	+0.069	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

SMIM23 by TTC29 expression — SKIN

Explore this box plot interactively →