TTC26

Across TCGA pan-cancer cohorts, TTC26 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TTC26 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TTC26 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TTC26 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where TTC26 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	0.534	1.000	.044	4	view →
LUAD	DFS	Median	All	0.885	1.000	.009	4	view →
CCRCC	OS	Median	All	1.000	0.680	.016	4	view →
LSCC	OS	Quartile	All	0.880	1.000	.022	3	view →
GBM	OS	Quartile	All	0.754	0.907	.024	3	view →
PDAC	OS	Median	IV	0.405	0.828	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TTC26–UCEC (OS)

Open the UCEC breakdown →