Across TCGA patient cohorts, TTC25 protein abundance is significantly associated with the RNA expression of many other genes, with 4,857 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC25-associated genes across cancer lineages are BBOF1, DNAI1, and STOML3. Each is linked with TTC25 in more than 4 cancer types. Because this analysis shows association rather than direction, both TTC25-to-partner and partner-to-TTC25 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC25→partner) and Y-score (partner→TTC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BBOF1 →	+1.027	+1.055	<.001	<.001	3	5
UCEC	DNAI1 →	+2.462	+1.192	<.001	<.001	3	5
UCEC	STOML3 →	+2.269	+1.151	<.001	<.001	3	5
UCEC	WDR38 →	+2.274	+1.132	<.001	<.001	3	5
UCEC	PIH1D2 →	+0.822	+1.019	<.001	<.001	3	5
UCEC	CFAP52 →	+1.293	+0.795	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,857 associations by consensus.

Exploration

TTC25 survival (RNA) · tumor vs normal (RNA) · all TTC25 data types