Across TCGA patient cohorts, TTC23L RNA expression is significantly associated with the protein abundance of many other proteins, with 13,298 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTC23L-associated proteins across cancer lineages are LZTFL1, WDR35, and IFT122. Each is linked with TTC23L in more than 5 cancer types. Because this analysis shows association rather than direction, both TTC23L-to-partner and partner-to-TTC23L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC23L→partner) and Y-score (partner→TTC23L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LZTFL1 →	+0.551	+0.769	<.001	<.001	3	6
BRCA	WDR35 →	+0.367	+0.806	<.001	<.001	3	6
BRCA	IFT122 →	+0.369	+0.860	<.001	<.001	3	6
HNSC	ERI3 →	+0.291	+0.737	<.001	<.001	3	5
HNSC	HELZ2 →	-0.439	-0.618	<.001	.001	3	5
BRCA	WDR19 →	+0.445	+0.860	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,298 associations by consensus.

Exploration

TTC23L survival (RNA) · tumor vs normal (RNA) · all TTC23L data types