TTC23L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TTC23L mutation is significantly associated with the RNA expression of many other genes, with 2,579 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC23L-associated genes across cancer lineages are CDY3P, MIR6075, and CYFIP1. Each is linked with TTC23L in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC23L-to-partner and partner-to-TTC23L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC23L→partner) and Y-score (partner→TTC23L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACDY3P →+0.016+7.471<.001.00832
UCECMIR6075 →+0.208+2.178.001<.00132
UCECCYFIP1 →+0.426+2.721.002.00332
UCECIGHV2-70 →+1.716+3.807<.001<.00132
UCECCCL18 →+1.667+3.169<.001<.00132
UCECUHRF1 →+0.923+2.010<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,579 associations by consensus.

Exploration