TTC23

Across TCGA patient cohorts, TTC23 protein abundance is significantly associated with the RNA expression of many other genes, with 1,046 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTC23-associated genes across cancer lineages are ANKRD16, AMIGO2, and NDNF. Each is linked with TTC23 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC23-to-partner and partner-to-TTC23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC23 versus ANKRD16 in LSCC, with a Pearson correlation of -0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC23→partner) and Y-score (partner→TTC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANKRD16 →	-1.035	-0.584	.002	.001	3	2
GBM	AMIGO2 →	+2.380	+0.430	.003	.005	3	2
LSCC	NDNF →	+2.295	+0.583	.001	.001	3	2
LSCC	LGALS1 →	+1.649	+0.584	.003	.001	3	1
LSCC	TAB1 →	-0.532	-0.584	.007	.001	3	1
LSCC	COCH →	-2.833	-0.569	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,046 associations by consensus.

TTC23 vs ANKRD16 — LSCC

Explore this scatter interactively →