TTC17

Across TCGA patient cohorts, TTC17 protein abundance is significantly associated with the RNA expression of many other genes, with 5,959 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTC17-associated genes across cancer lineages are RPN2, ERGIC3, and STT3A. Each is linked with TTC17 in more than 2 cancer types. Because this analysis shows association rather than direction, both TTC17-to-partner and partner-to-TTC17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC17 versus RPN2 in CCRCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC17→partner) and Y-score (partner→TTC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RPN2 →	+0.344	+0.245	.002	<.001	3	3
LUAD	ERGIC3 →	+0.338	+0.210	<.001	<.001	3	3
CCRCC	STT3A →	+0.447	+0.240	<.001	<.001	3	3
GBM	SLC14A1 →	-1.895	-0.255	<.001	<.001	3	3
CCRCC	HSP90B1 →	+0.655	+0.250	<.001	<.001	3	3
LUAD	LMAN2 →	+0.459	+0.260	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,959 associations by consensus.

TTC17 vs RPN2 — CCRCC

Explore this scatter interactively →