TTC16

Across TCGA cell cohorts, TTC16 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,910 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC16-associated GO terms across cancer lineages are Fatty acid oxidation, Transport along microtubule, and Primary alcohol biosynthetic process. Each is linked with TTC16 in more than 7 cancer types. Because this analysis shows association rather than direction, both TTC16-to-partner and partner-to-TTC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid oxidation grouped by TTC16-low versus TTC16-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC16→partner) and Y-score (partner→TTC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Fatty acid oxidation →	+0.055	+0.086	<.001	.003	3	7
BLOOD_Leukemia	Transport along microtubule →	+0.040	+0.669	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Primary alcohol biosynthetic process →	-0.267	-0.034	.003	.003	3	6
SOFT_TISSUE	Negative regulation of ruffle assembly →	+0.131	+0.056	.005	.007	3	6
BREAST	Fatty acid beta-oxidation using acyl-CoA dehydrogenase →	+0.108	+0.078	<.001	.005	3	6
BREAST	Fatty acid beta-oxidation →	+0.056	+0.094	.008	.005	1	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,910 associations by consensus.

Fatty acid oxidation by TTC16 expression — OVARY

Explore this box plot interactively →