TTC13

Across TCGA cell cohorts, TTC13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,072 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TTC13-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum membrane, Nuclear pore complex assembly, and Negative regulation of CD8-positive, alpha-beta T cell differentiation. Each is linked with TTC13 in more than 12 cancer types. Because this analysis shows association rather than direction, both TTC13-to-partner and partner-to-TTC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum membrane grouped by TTC13-low versus TTC13-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC13→partner) and Y-score (partner→TTC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment of protein localization to endoplasmic reticulum membrane →	+0.116	+0.714	<.001	.009	2	13
SOFT_TISSUE	Nuclear pore complex assembly →	+0.148	+1.020	<.001	<.001	3	11
LARGE_INTESTINE	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.174	+0.969	<.001	<.001	3	11
BONE	RNA 3'-end processing →	+0.056	+0.579	.003	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.071	+1.076	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromatin organization →	+0.125	+1.017	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,072 associations by consensus.

Establishment of protein localization to endoplasmic reticulum membrane by TTC13 expression — URINARY_TRACT

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