TTC12

Across TCGA patient cohorts, TTC12 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,458 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTC12-associated proteins across cancer lineages are IFT46, RNF214, and IFT22. Each is linked with TTC12 in more than 5 cancer types. Because this analysis shows association rather than direction, both TTC12-to-partner and partner-to-TTC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC12 versus IFT46 in OV, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC12→partner) and Y-score (partner→TTC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IFT46 →	+0.510	+0.517	<.001	<.001	3	6
OV	RNF214 →	+0.231	+0.639	<.001	<.001	3	5
OV	IFT22 →	+0.355	+0.792	.001	<.001	3	5
LSCC	UBE4A →	+0.245	+0.465	<.001	<.001	3	5
CCRCC	PLEK →	-0.416	-0.382	<.001	.001	3	4
BRCA	RAD50 →	+0.329	+0.581	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,458 associations by consensus.

TTC12 vs IFT46 — OV

Explore this scatter interactively →