TTC12

Across TCGA cell cohorts, TTC12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,185 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TTC12-associated GO terms across cancer lineages are Flagellated sperm motility, Cilium movement involved in cell motility, and Sperm motility. Each is linked with TTC12 in more than 8 cancer types. Because this analysis shows association rather than direction, both TTC12-to-partner and partner-to-TTC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by TTC12-low versus TTC12-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC12→partner) and Y-score (partner→TTC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Flagellated sperm motility →	-0.099	-1.327	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.096	-1.064	<.001	<.001	3	9
LUNG_SCLC	Sperm motility →	-0.099	-1.327	<.001	.003	3	9
LUNG_SCLC	Intraciliary anterograde transport →	+0.091	+1.116	.005	.004	2	9
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.090	-1.064	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.090	-1.064	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,185 associations by consensus.

Flagellated sperm motility by TTC12 expression — LUNG_SCLC

Explore this box plot interactively →