TST

Across TCGA patient cohorts, TST mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TST-associated genes across cancer lineages are Platelets, mv Endothelial cells, and lymphatic Endothelial cells. Each is linked with TST in more than 1 cancer types. Because this analysis shows association rather than direction, both TST-to-partner and partner-to-TST results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by TST-low versus TST-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TST→partner) and Y-score (partner→TST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Platelets →	+0.019	+2.450	.015	.049	3	1
UCEC	mv Endothelial cells →	-0.028	-2.311	.020	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.025	-2.959	.039	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by TST expression — BLCA

Explore this box plot interactively →