TSSK4

Across TCGA cell cohorts, TSSK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,689 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSSK4-associated GO terms across cancer lineages are Regulation of mRNA processing, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with TSSK4 in more than 18 cancer types. Because this analysis shows association rather than direction, both TSSK4-to-partner and partner-to-TSSK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by TSSK4-low versus TSSK4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSK4→partner) and Y-score (partner→TSSK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA processing →	+0.094	+1.048	<.001	<.001	3	19
LUNG_SCLC	Promoter clearance during DNA-templated transcription →	+0.124	+0.682	.001	.004	2	19
LUNG_SCLC	RNA polymerase II promoter clearance →	+0.124	+0.682	.001	.004	2	19
BONE	Negative regulation of gene expression, epigenetic →	+0.102	+1.255	<.001	<.001	3	18
OESOPHAGUS	Regulation of mRNA splicing, via spliceosome →	+0.102	+1.112	.001	.005	3	18
PANCREAS	Positive regulation of DNA metabolic process →	+0.074	+1.187	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,689 associations by consensus.

Regulation of mRNA processing by TSSK4 expression — SOFT_TISSUE

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