Across TCGA pan-cancer cohorts, TSSK1B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TSSK1B data layer compared with 16 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TSSK1B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TSSK1B expression acts as an unfavorable survival marker.

BRCA, READ, and PRAD are the cancer types where TSSK1B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.335	0.924	.005	36	view →
READ	OS	Median	III,IV	0.111	0.903	<.001	21	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TSSK1B tumor-vs-normal RNA expression · all TSSK1B data types