Across TCGA pan-cancer cohorts, TSSK1B RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TSSK1B’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TSSK1B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TSSK1B is over-expressed in tumor.
LUSC are the cancer types where TSSK1B tumor–normal differential expression is most reproducible.