Across TCGA patient cohorts, TSSK1B mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TSSK1B-associated genes across cancer lineages are ATM, HER3_pY1289, and cIAP. Each is linked with TSSK1B in more than 2 cancer types. Because this analysis shows association rather than direction, both TSSK1B-to-partner and partner-to-TSSK1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSK1B→partner) and Y-score (partner→TSSK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATM →	-0.370	-3.321	.010	.009	3	3
COAD	HER3_pY1289 →	+0.078	+2.824	.026	.034	3	2
COAD	cIAP →	+0.108	+1.866	.022	.014	3	2
COAD	Cyclin-D1 →	+0.109	+2.824	.023	.034	3	2
SKCM	p27_pT198 →	+0.110	+3.186	.038	.009	3	2
SKCM	CDK1 →	+0.181	+3.169	.011	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

TSSK1B survival (RNA) · tumor vs normal (RNA) · all TSSK1B data types