TSSK1B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TSSK1B mutation is significantly associated with the RNA expression of many other genes, with 230 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSSK1B-associated genes across cancer lineages are GCAT, CBY1, and JOSD1. Each is linked with TSSK1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TSSK1B-to-partner and partner-to-TSSK1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSK1B→partner) and Y-score (partner→TSSK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGCAT →+1.103+3.169.002.00931
LARGE_INTESTINECBY1 →+0.672+2.596<.001.00231
LARGE_INTESTINEJOSD1 →+0.515+3.169.003.00931
LARGE_INTESTINEETV7 →+0.921+3.169.006.00931
LARGE_INTESTINECBX7 →+0.741+2.628.005.00231
LARGE_INTESTINECHMP4B →-0.610-2.541.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 230 associations by consensus.

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