TSSK1A

Across TCGA pan-cancer cohorts, TSSK1A RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TSSK1A’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TSSK1A RNA is repressed in tumor relative to normal tissue. In most cancer types TSSK1A is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, KIRC, and LIHC are the cancer types where TSSK1A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSSK1A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.609	<.001	11	view →
KIRC	All	All	+0.116	<.001	9	view →
LIHC	All	All	+0.139	<.001	6	view →
LUAD	Male	II,III,IV	−0.273	.001	5	view →
COAD	Female	III,IV	−0.122	.005	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TSSK1A–THCA

Open the THCA breakdown →