TSR3

Across TCGA cell cohorts, TSR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,917 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TSR3-associated GO terms across cancer lineages are CAMP/PKA signal transduction, Regulation of Golgi inheritance, and Peptidyl-methionine modification. Each is linked with TSR3 in more than 13 cancer types. Because this analysis shows association rather than direction, both TSR3-to-partner and partner-to-TSR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMP/PKA signal transduction grouped by TSR3-low versus TSR3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSR3→partner) and Y-score (partner→TSR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CAMP/PKA signal transduction →	+0.188	+0.889	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.197	+0.881	<.001	<.001	2	14
OESOPHAGUS	Peptidyl-methionine modification →	+0.192	+0.720	.004	.004	2	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagosome maturation →	+0.132	+0.817	.002	.004	3	12
BLOOD_Myeloma	rRNA pseudouridine synthesis →	+0.141	+1.057	<.001	.001	3	12
SKIN	Enzyme-directed rRNA pseudouridine synthesis →	+0.127	+0.822	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,917 associations by consensus.

CAMP/PKA signal transduction by TSR3 expression — URINARY_TRACT

Explore this box plot interactively →