TSR3

Across TCGA cell cohorts, TSR3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,675 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSR3-associated genes across cancer lineages are CRLF3, TOM1L1, and CHCHD4. Each is linked with TSR3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TSR3-to-partner and partner-to-TSR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSR3 versus CRLF3 in OVARY, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSR3→partner) and Y-score (partner→TSR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CRLF3 →	+0.952	+1.234	<.001	.008	3	7
STOMACH	TOM1L1 →	+0.890	+0.804	.009	.004	3	6
STOMACH	CHCHD4 →	+0.872	+1.088	<.001	.001	3	6
STOMACH	ATP5F1D →	+1.388	+1.150	.002	.001	3	6
UPPER_AERODIGESTIVE_TRACT	DBR1 →	+0.834	+1.034	.001	.001	3	6
BLOOD_Leukemia	CIT →	+1.105	+0.365	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,675 associations by consensus.

TSR3 vs CRLF3 — OVARY

Explore this scatter interactively →