TSR1

Across TCGA patient cohorts, TSR1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,761 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TSR1-associated genes across cancer lineages are MIS12, POLH, and TVP23B. Each is linked with TSR1 in more than 33 cancer types. Because this analysis shows association rather than direction, both TSR1-to-partner and partner-to-TSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSR1 versus MIS12 in UVM, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSR1→partner) and Y-score (partner→TSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	MIS12 →	+1.218	+0.908	<.001	<.001	3	34
KICH	POLH →	+1.194	+0.889	<.001	<.001	3	34
THYM	TVP23B →	+1.114	+0.677	<.001	<.001	3	34
SCLC	PRPF8 →	+1.259	+0.776	<.001	<.001	3	34
KIRP	SMCR8 →	+1.155	+0.982	<.001	<.001	3	34
SCLC	TOP3A →	+1.091	+0.827	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,761 associations by consensus.

TSR1 vs MIS12 — UVM

Explore this scatter interactively →