Across TCGA cell cohorts, TSPYL4 mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPYL4-associated genes across cancer lineages are Nutlin-3a (-), Carmustine, and 123138. Each is linked with TSPYL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPYL4-to-partner and partner-to-TSPYL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL4→partner) and Y-score (partner→TSPYL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nutlin-3a (-) →	+0.815	+2.646	.026	.047	3	1
LARGE_INTESTINE	Carmustine →	+0.376	+2.649	.032	.046	3	1
LARGE_INTESTINE	123138 →	+0.367	+2.649	.012	.046	3	1
LARGE_INTESTINE	743380 →	+0.693	+2.649	.011	.046	3	1
LARGE_INTESTINE	Bleomycin →	+0.479	+2.649	.015	.046	2	1
LARGE_INTESTINE	Nelarabine →	+0.302	+2.649	.021	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

TSPYL4 survival (RNA) · tumor vs normal (RNA) · all TSPYL4 data types