Across TCGA patient cohorts, TSPYL2 mutation is significantly associated with the RNA expression of many other genes, with 6,312 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPYL2-associated genes across cancer lineages are MIR1229, MIR1224, and LINC02559. Each is linked with TSPYL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSPYL2-to-partner and partner-to-TSPYL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL2→partner) and Y-score (partner→TSPYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MIR1229 →	+0.454	+4.653	<.001	.007	3	3
BRCA	MIR1224 →	+0.201	+5.725	<.001	.001	3	3
CESC	LINC02559 →	+1.025	+5.342	<.001	.002	3	2
CESC	HMGB3P12 →	+0.076	+5.144	<.001	.003	3	2
UCEC	LSM10 →	+0.436	+2.402	<.001	<.001	3	2
UCEC	GINS3 →	+0.585	+2.191	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,312 associations by consensus.

Exploration

TSPYL2 survival (RNA) · tumor vs normal (RNA) · all TSPYL2 data types