Across TCGA patient cohorts, TSPYL1 mutation is significantly associated with the RNA expression of many other genes, with 1,008 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPYL1-associated genes across cancer lineages are SLC25A51P3, LINC02277, and MTND2P6. Each is linked with TSPYL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPYL1-to-partner and partner-to-TSPYL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL1→partner) and Y-score (partner→TSPYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC25A51P3 →	+0.138	+5.602	.003	.004	3	2
CESC	LINC02277 →	+0.077	+3.996	.003	.005	3	2
BLCA	MTND2P6 →	+0.078	+4.289	<.001	.007	3	2
CESC	RNY4P36 →	+0.430	+3.944	.005	.007	3	2
UCEC	MIR4749 →	+0.152	+3.928	<.001	.007	3	2
UCEC	SC4MOP →	+0.113	+3.868	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,008 associations by consensus.

Exploration

TSPYL1 survival (RNA) · tumor vs normal (RNA) · all TSPYL1 data types