long intergenic non-protein coding RNA 2277Genealiases: []
Q-omics provides the consensus-scored LINC02277 profile across patient tissues and cancer cell-line models. LINC02277 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, LINC02277 is differentially expressed in 4, with the highest sampling consensus in LUAD. Additionally, LINC02277 RNA expression shows 8,691 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight THCA, LUAD, and TGCT as cancer lineages where LINC02277 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02277 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02277 survival associations across molecular data types. LINC02277 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02277 RNA expression–survival associations across cancer types. High LINC02277 expression shows unfavorable associations in THCA, KIRP, LUSC, ESCA, COAD and SKCM. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for LINC02277 RNA expression.
This table summarizes LINC02277 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02277. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02277 shows lower tumor expression in LUAD, LUSC and KIRC and higher tumor expression in UCEC. The LUAD box plot shows higher LINC02277 RNA expression in normal versus tumor tissue (log2 FC = −0.126, t-test p = .010).
This table shows molecular features associated with LINC02277 in patient tissues and cancer cell lines. In patient samples, LINC02277 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
