LINC02277

Across TCGA pan-cancer cohorts, LINC02277 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LINC02277 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher LINC02277 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02277 expression acts as an unfavorable survival marker, although some lineages such as PAAD and MESO show a favorable association.

THCA, KIRP, and LUSC are the cancer types where LINC02277 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Quartile	II,III,IV	0.856	0.979	<.001	97	view →
KIRP	OS	Tertile	All	0.246	0.741	<.001	84	view →
LUSC	DFS	Tertile	II,III,IV	0.543	0.739	.004	63	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	56	view →
COAD	OS	Tertile	II,III,IV	0.414	0.801	.002	42	view →
SKCM	DFS	Tertile	All	0.457	0.685	<.001	39	view →
KIRC	OS	Tertile	All	0.688	0.817	.031	30	view →
PAAD	DFS	Tertile	All	0.731	0.432	.003	30	view →
MESO	OS	Tertile	All	0.881	0.357	.009	27	view →
READ	DFS	Tertile	III,IV	0.351	0.785	.003	27	view →
HNSC	OS	Tertile	III,IV	0.217	0.565	.009	18	view →
STAD	OS	Median	IV	0.682	0.249	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LINC02277–THCA (OS)

Open the THCA breakdown →