TSPY4

Across TCGA patient cohorts, TSPY4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,853 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible TSPY4-associated GO terms across cancer lineages are Methylation, RNA methylation, and Cytosolic ribosome assembly. Each is linked with TSPY4 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSPY4-to-partner and partner-to-TSPY4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by TSPY4-low versus TSPY4-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPY4→partner) and Y-score (partner→TSPY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Methylation →	+0.097	+0.014	<.001	.001	3	3
LUSC	RNA methylation →	+0.099	+0.012	<.001	.004	2	3
LUSC	Cytosolic ribosome assembly →	+0.064	+0.016	<.001	.004	3	2
LUSC	Polyadenylation-dependent RNA catabolic process →	+0.085	+0.012	<.001	.004	3	2
LUSC	Double-strand break repair via nonhomologous end joining →	+0.083	+0.021	<.001	.004	3	2
LUSC	RNA modification →	+0.092	+0.013	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,853 associations by consensus.

Methylation by TSPY4 expression — LUSC

Explore this box plot interactively →