TSPY4

Across TCGA pan-cancer cohorts, TSPY4 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated TSPY4 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TSPY4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TSPY4 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

UCEC, LIHC, and HNSC are the cancer types where TSPY4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.198	0.873	<.001	108	view →
LIHC	DFS	Tertile	II,III,IV	0.095	0.431	.003	54	view →
HNSC	OS	Tertile	IV	0.469	0.739	.020	36	view →
SKCM	DFS	Tertile	All	0.581	0.199	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TSPY4–UCEC (OS)

Open the UCEC breakdown →