TSPY2

Across TCGA cell cohorts, TSPY2 RNA expression is significantly associated with the mutation status of many other genes, with 90 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPY2-associated genes across cancer lineages are ATP2B2, GIGYF2, and LRRC59. Each is linked with TSPY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPY2-to-partner and partner-to-TSPY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP2B2 grouped by TSPY2-low versus TSPY2-high in OVARY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPY2→partner) and Y-score (partner→TSPY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ATP2B2 →	+4.222	+0.010	.006	<.001	3	2
LARGE_INTESTINE	GIGYF2 →	+2.824	+0.024	.001	.004	3	2
SOFT_TISSUE	LRRC59 →	+5.369	+0.022	.004	<.001	3	1
SOFT_TISSUE	POLR3A →	+4.369	+0.016	.008	.001	3	1
SOFT_TISSUE	GAA →	+4.369	+0.029	.008	<.001	3	1
SOFT_TISSUE	ZNF101 →	+5.369	+0.022	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

ATP2B2 by TSPY2 expression — OVARY

Explore this box plot interactively →