TSPOAP1

Across TCGA cell cohorts, TSPOAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,432 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPOAP1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of protein localization to nucleus. Each is linked with TSPOAP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TSPOAP1-to-partner and partner-to-TSPOAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TSPOAP1-low versus TSPOAP1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPOAP1→partner) and Y-score (partner→TSPOAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.094	+1.356	<.001	.003	3	11
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.123	+1.726	<.001	.001	3	11
OVARY	Regulation of protein localization to nucleus →	+0.072	+1.152	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.931	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular transport →	+0.043	+0.516	<.001	.005	3	10
BREAST	Regulation of myoblast fusion →	+0.101	+1.602	<.001	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,432 associations by consensus.

Negative regulation of myoblast fusion by TSPOAP1 expression — BREAST

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