TSPOAP1-AS1

Across TCGA pan-cancer cohorts, TSPOAP1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TSPOAP1-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TSPOAP1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TSPOAP1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, PAAD, and UVM are the cancer types where TSPOAP1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.766	0.627	<.001	134	view →
PAAD	OS	Median	All	0.502	0.268	<.001	88	view →
UVM	DFS	Median	All	0.434	0.699	.001	75	view →
LUAD	OS	Median	All	0.753	0.620	<.001	56	view →
COAD	OS	Tertile	All	0.383	0.730	<.001	47	view →
BRCA	OS	Median	III,IV	0.892	0.766	.005	44	view →
SKCM	OS	Median	All	0.926	0.804	.005	38	view →
BLCA	OS	Quartile	All	0.775	0.595	.002	37	view →
ACC	DFS	Tertile	II,III,IV	0.330	0.678	.005	35	view →
ESCA	OS	Tertile	II,III,IV	0.692	0.389	.001	32	view →
READ	OS	Median	All	1.000	0.851	.002	29	view →
LGG	OS	Median	All	0.934	0.856	<.001	28	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TSPOAP1-AS1–HNSC (DFS)

Open the HNSC breakdown →