TSPOAP1-AS1

Across TCGA pan-cancer cohorts, TSPOAP1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TSPOAP1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TSPOAP1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TSPOAP1-AS1 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

BLCA, COAD, and THCA are the cancer types where TSPOAP1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSPOAP1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−1.065	<.001	11	view →
COAD	All	IV	+1.212	<.001	9	view →
THCA	All	All	−0.410	<.001	9	view →
KIRC	Male	II,III,IV	+0.342	<.001	9	view →
UCEC	All	All	−0.626	<.001	8	view →
LUSC	All	All	−0.335	<.001	7	view →
KICH	Male	All	−0.316	<.001	6	view →
LUAD	Female	II,III,IV	−0.371	<.001	4	view →
LIHC	All	II,III,IV	+0.141	.013	4	view →
CHOL	All	All	+0.761	.001	3	view →
READ	All	All	+0.798	.025	2	view →
PRAD	All	All	−0.377	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TSPOAP1-AS1–BLCA

Open the BLCA breakdown →