TSPAN9

Across TCGA patient cohorts, TSPAN9 mutation is significantly associated with the RNA expression of many other genes, with 675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN9-associated genes across cancer lineages are RNU6-1149P, RNU7-4P, and MIR5583-1. Each is linked with TSPAN9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN9-to-partner and partner-to-TSPAN9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1149P grouped by TSPAN9-low versus TSPAN9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN9→partner) and Y-score (partner→TSPAN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1149P →	+0.663	+4.951	<.001	.002	3	2
COAD	RNU7-4P →	+0.715	+5.003	<.001	.004	3	2
COAD	MIR5583-1 →	+0.515	+5.917	<.001	.001	3	2
PRAD	HMGB3P23 →	+0.069	+7.939	<.001	.008	3	2
UCEC	RNY1P8 →	+0.141	+2.868	.006	.009	3	2
UCEC	BNIP3P4 →	+0.053	+2.397	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 675 associations by consensus.

RNU6-1149P by TSPAN9 expression — COAD

Explore this box plot interactively →