TSPAN8

Across TCGA cell cohorts, TSPAN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,361 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN8-associated GO terms across cancer lineages are Response to alcohol, Golgi vesicle transport, and Lipid oxidation. Each is linked with TSPAN8 in more than 6 cancer types. Because this analysis shows association rather than direction, both TSPAN8-to-partner and partner-to-TSPAN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to alcohol grouped by TSPAN8-low versus TSPAN8-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN8→partner) and Y-score (partner→TSPAN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to alcohol →	+0.085	+5.060	<.001	<.001	3	7
LUNG_SCLC	Golgi vesicle transport →	+0.046	+2.413	.004	.001	3	7
LIVER	Lipid oxidation →	+0.099	+3.725	<.001	.001	3	7
LIVER	Medium-chain fatty acid catabolic process →	+0.275	+3.530	<.001	<.001	3	7
LIVER	Lysosomal transport →	+0.079	+4.448	<.001	<.001	3	7
BREAST	Protein localization to vacuole →	+0.038	+1.108	.008	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,361 associations by consensus.

Response to alcohol by TSPAN8 expression — STOMACH

Explore this box plot interactively →