TSPAN6

Across TCGA cell cohorts, TSPAN6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,333 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TSPAN6-associated GO terms across cancer lineages are Metanephric proximal tubule development, Regulation of syncytium formation by plasma membrane fusion, and Regulation of mRNA processing. Each is linked with TSPAN6 in more than 8 cancer types. Because this analysis shows association rather than direction, both TSPAN6-to-partner and partner-to-TSPAN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metanephric proximal tubule development grouped by TSPAN6-low versus TSPAN6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN6→partner) and Y-score (partner→TSPAN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Metanephric proximal tubule development →	-0.240	-1.134	<.001	.001	3	9
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+1.194	<.001	<.001	3	9
OESOPHAGUS	Regulation of mRNA processing →	+0.080	+1.833	.007	.008	3	8
OVARY	RNA splicing, via transesterification reactions →	+0.057	+1.129	<.001	<.001	3	8
OVARY	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.056	+1.030	.001	<.001	3	8
OVARY	mRNA splicing, via spliceosome →	+0.056	+1.030	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,333 associations by consensus.

Metanephric proximal tubule development by TSPAN6 expression — SOFT_TISSUE

Explore this box plot interactively →