Across TCGA patient cohorts, TSPAN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSPAN4-associated proteins across cancer lineages are DPYD, VIM, and PCOLCE. Each is linked with TSPAN4 in more than 6 cancer types. Because this analysis shows association rather than direction, both TSPAN4-to-partner and partner-to-TSPAN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN4→partner) and Y-score (partner→TSPAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DPYD →	+0.720	+0.399	.001	.001	3	7
PDAC	VIM →	+0.455	+0.523	<.001	<.001	3	7
BRCA	PCOLCE →	+0.788	+0.744	<.001	<.001	3	7
BRCA	ISLR →	+0.757	+0.682	<.001	.002	3	6
BRCA	KANK2 →	+0.508	+0.784	<.001	<.001	3	6
BRCA	LRP1 →	+0.606	+0.746	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,407 associations by consensus.

Exploration

TSPAN4 survival (RNA) · tumor vs normal (RNA) · all TSPAN4 data types