TSPAN19

Across TCGA cell cohorts, TSPAN19 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,115 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TSPAN19-associated GO terms across cancer lineages are Cytoplasmic translation, Regulation of late endosome to lysosome transport, and Regulation of vacuolar transport. Each is linked with TSPAN19 in more than 7 cancer types. Because this analysis shows association rather than direction, both TSPAN19-to-partner and partner-to-TSPAN19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by TSPAN19-low versus TSPAN19-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN19→partner) and Y-score (partner→TSPAN19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cytoplasmic translation →	+0.069	+0.238	<.001	.005	3	8
URINARY_TRACT	Regulation of late endosome to lysosome transport →	-0.150	-0.444	<.001	.008	3	8
URINARY_TRACT	Regulation of vacuolar transport →	-0.150	-0.444	<.001	.008	3	8
LUNG_SCLC	Positive regulation of chromosome organization →	+0.041	+0.906	.002	<.001	3	8
STOMACH	Positive regulation of protein localization to mitochondrion →	+0.106	+0.490	<.001	.009	3	7
SOFT_TISSUE	Macroautophagy →	+0.035	+0.269	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,115 associations by consensus.

Cytoplasmic translation by TSPAN19 expression — PANCREAS

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