TSPAN19

Across TCGA cell cohorts, TSPAN19 mutation is significantly associated with the mutation status of many other genes, with 133 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TSPAN19-associated genes across cancer lineages are LPXN, ACRBP, and TOB1. Each is linked with TSPAN19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN19-to-partner and partner-to-TSPAN19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LPXN grouped by TSPAN19-low versus TSPAN19-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN19→partner) and Y-score (partner→TSPAN19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	LPXN →	+5.297	+5.297	.004	.004	1	2
BREAST	ACRBP →	+5.297	+5.297	.004	.004	1	2
BREAST	TOB1 →	+5.297	+5.297	.004	.004	1	2
BREAST	NPAS4 →	+5.297	+5.297	.004	.004	1	2
BREAST	PRKAR1B →	+5.297	+5.297	.004	.004	1	1
BREAST	STK40 →	+5.297	+5.297	.004	.004	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

LPXN by TSPAN19 expression — BREAST

Explore this box plot interactively →