TSPAN17

Across TCGA cell cohorts, TSPAN17 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,331 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TSPAN17-associated GO terms across cancer lineages are Autophagosome organization, Positive regulation of translational initiation, and Regulation of stress-activated protein kinase signaling cascade. Each is linked with TSPAN17 in more than 12 cancer types. Because this analysis shows association rather than direction, both TSPAN17-to-partner and partner-to-TSPAN17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by TSPAN17-low versus TSPAN17-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN17→partner) and Y-score (partner→TSPAN17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Autophagosome organization →	+0.057	+0.739	<.001	<.001	3	13
PANCREAS	Positive regulation of translational initiation →	+0.107	+0.723	<.001	.003	3	12
LUNG_NSCLC_LUAD	Regulation of stress-activated protein kinase signaling cascade →	+0.121	+1.005	<.001	<.001	3	12
BONE	Positive regulation of supramolecular fiber organization →	+0.092	+0.912	<.001	<.001	3	12
BLOOD_Myeloma	Protein-RNA covalent cross-linking repair →	+0.140	+1.290	<.001	.001	3	11
LIVER	Dephosphorylation →	+0.060	+0.877	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,331 associations by consensus.

Autophagosome organization by TSPAN17 expression — OVARY

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