TSPAN13

Across TCGA patient cohorts, TSPAN13 mutation is significantly associated with the RNA expression of many other genes, with 296 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN13-associated genes across cancer lineages are RNU1-49P, RNU6-275P, and MIR1283-2. Each is linked with TSPAN13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN13-to-partner and partner-to-TSPAN13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-49P grouped by TSPAN13-low versus TSPAN13-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN13→partner) and Y-score (partner→TSPAN13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU1-49P →	+0.379	+4.671	<.001	.004	3	2
SKCM	RNU6-275P →	+0.248	+4.302	<.001	.007	3	2
COAD	MIR1283-2 →	+0.392	+7.741	<.001	.009	3	1
HNSC	RNU6-664P →	+0.338	+7.954	<.001	.008	3	1
HNSC	RNU6-978P →	+0.347	+7.954	<.001	.008	3	1
HNSC	RNU1-139P →	+0.239	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 296 associations by consensus.

RNU1-49P by TSPAN13 expression — SKCM

Explore this box plot interactively →