TSPAN12

Across TCGA patient cohorts, TSPAN12 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,426 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TSPAN12-associated proteins across cancer lineages are PPP1R9A_S840, NOSTRIN, and DDAH1. Each is linked with TSPAN12 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSPAN12-to-partner and partner-to-TSPAN12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN12 versus PPP1R9A_S840 in HNSC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN12→partner) and Y-score (partner→TSPAN12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPP1R9A_S840 →	+1.345	+0.844	<.001	<.001	3	6
CCRCC	NOSTRIN →	+0.602	+1.235	<.001	.001	3	5
LUAD	DDAH1 →	+0.606	+0.745	<.001	<.001	3	5
HNSC	CLDN3 →	+0.987	+1.240	.006	<.001	3	5
LUAD	PLOD1 →	-0.371	-0.732	.001	.001	3	4
GBM	ITGB2 →	-0.490	-0.877	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,426 associations by consensus.

TSPAN12 vs PPP1R9A_S840 — HNSC

Explore this scatter interactively →