TSPAN12

Across TCGA cell cohorts, TSPAN12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,293 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TSPAN12-associated GO terms across cancer lineages are Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Nucleoside triphosphate biosynthetic process, and Response to lithium ion. Each is linked with TSPAN12 in more than 7 cancer types. Because this analysis shows association rather than direction, both TSPAN12-to-partner and partner-to-TSPAN12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by TSPAN12-low versus TSPAN12-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN12→partner) and Y-score (partner→TSPAN12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.118	+2.800	.008	<.001	3	8
BLOOD_Lymphoma	Nucleoside triphosphate biosynthetic process →	+0.076	+1.030	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Response to lithium ion →	+0.191	+1.947	<.001	<.001	3	8
STOMACH	Regulation of thrombin-activated receptor signaling pathway →	-1.217	-1.975	.001	.001	3	8
STOMACH	Negative regulation of thrombin-activated receptor signaling pathway →	-1.217	-1.975	.001	.001	3	8
SOFT_TISSUE	Acetylcholine metabolic process →	+1.158	+2.553	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,293 associations by consensus.

Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by TSPAN12 expression — LIVER

Explore this box plot interactively →